Product Science


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IMM-124E improves metabolic endotoxemia and markers of liver injury in non-alcoholic steatohepatitis
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Hyperimmune bovine colostrum reduces gastrointestinal carriage of Uropathogenic E.coli. Human Vaccines & Immunotherapeutics 2018.
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Bioactive Immune Components of Anti-Diarrheagenic Enterotoxigenic Escherichia coli Hyperimmune Bovine Colostrum Products
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Hutton et al. Bovine antibodies targeting primary and recurrent Clostridium difficle disease are potent antibiotic alternative. Scientific Reports 2017;7: 3665
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Otto W, Najnigier B, Stelmasiak T and Robins-Browne RM. Randomized control trials using a tablet formulation of hyperimmune bovine colostrum to prevent diarrhea caused by enterotoxigenic Escherichia coli in volunteers. Scandinavian J Gastro. 2011;46:862-868
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Quigley EM, Stanton C and Murphy EF. The gut microbiota and the liver. Pathophysiological and clinical implications. J Hepatol. 2013;58: 1020-1027
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Frazier TH, DiBaise JK and McClain CJ. Gut microbiota, intestinal permeability, obesity-induced inflammation and liver injury. J Parenter Enteral Nutr. 2011; 35:14S
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Rescigno M. The intestinal epithelial barrier in the control of homeostasis and immunity. Trends Immunol. 2011; 32(6): 256-264
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Bringiotti R, Ierardi E, Lovero R, Losurdo G, Di Leo A, Principi M. Intestinal microbiota: The explosive mixture at the origin of inflammatory bowel disease? World J Gastrointest Pathophysiol. 2014 Nov 15;5(4):550-9.
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Grace E, Shaw C, Whelan K and Andreyez HJN. Small intestinal bacterial overgrowth – prevalence, clinical features, current and developing diagnostic tests, and treatment. Aliment Pharmacol Ther. 2013; 38: 674-688
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Pimentel M and Chang C. Inflammation and microflora. Gastroenterol Clin North Am. 2011; 40: 69-85
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Nolan JP. The role of intestinal endotoxin in liver injury: a long and evolving history. Hepatology. 2010; 52(5): 1829-1835
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Viladomiu M, Hontecillas R, Yuan L, Lu P and Bassaganya-Riera J. Nutritional protective mechanisms against gut inflammation. J Nutr Biochem. 2013; 24:929-939
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Roh YS and Seki E. Toll-like receptors in alcoholic liver disease, non-alcoholic steatohepatitis and carcinogenesis. J Gastroenterol Hepatol. 2013; 28(S1): 38-42
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Cesaro C, Tiso A, Del Prete A, Cariello R, Tuccillo C, Cotticelli G, del Vecchio Blanco C and Loguercio C. Gut microbiota and probiotics in chronic liver diseases. Dig Liver Dis. 2011; 43: 431-438